The mechanism of action of Fildena 150 mg is primarily related to its active ingredient, sildenafil citrate. Sildenafil citrate is a phosphodiesterase type 5 (PDE5) inhibitor, and its mechanism of action involves several steps:

Inhibition of PDE5: Sildenafil citrate works by inhibiting the enzyme phosphodiesterase type 5 (PDE5). PDE5 is responsible for breaking down cyclic guanosine monophosphate (cGMP), a molecule that promotes smooth muscle relaxation in the blood vessels of the penis during sexual arousal. By inhibiting PDE5, sildenafil increases the levels of cGMP, leading to enhanced smooth muscle relaxation and increased blood flow to the penis.

Enhanced Nitric Oxide (NO) Signaling: Sexual stimulation triggers the release of nitric oxide (NO) in the penis. NO activates an enzyme called guanylate cyclase, which increases the production of cGMP. Higher levels of cGMP lead to relaxation of smooth muscle cells in the penile arteries and corpus cavernosum, allowing for increased blood flow and the attainment and maintenance of an erection.

Erection Maintenance: By enhancing the effects of NO and increasing cGMP levels, sildenafil citrate helps to facilitate the erection process and maintain penile rigidity during sexual activity. It is important to note that sexual stimulation is still required for sildenafil citrate to be effective, as it does not directly cause erections but rather enhances the body's natural response to sexual stimulation.

Duration of Action: Sildenafil citrate has a relatively short half-life, typically ranging from 3 to 5 hours. However, its effects on erectile function can last for up to 4 to 6 hours after ingestion, allowing for a window of opportunity for sexual activity.

Learning about the mechanism of action of Fildena 150 mg can provide insights into how the medication works to treat erectile dysfunction and its effects on the body's physiological processes involved in the erection response. If you seek more detailed information, consulting medical literature or reliable sources on pharmacology and erectile dysfunction may be beneficial. Additionally, healthcare professionals, such as doctors or pharmacists, can provide explanations and guidance on the mechanism of action of Fildena 150 mg.


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